/* ==========================================================================
   PGxIQ Design System
   Professional Medical SaaS Stylesheet
   ========================================================================== */

/* --- 1. CSS Custom Properties (Design Tokens) --- */
:root {
  /* Primary Palette (Deep Blue Family) */
  --color-primary-900: #1a365d;
  --color-primary-800: #1e3d72;
  --color-primary-700: #2c5282;
  --color-primary-600: #2c5aa0;
  --color-primary-500: #3182ce;
  --color-primary-400: #4299e1;
  --color-primary-100: #ebf4ff;

  /* Neutrals (Cool Blue-Gray) */
  --color-bg-page: #f7fafc;
  --color-bg-surface: #ffffff;
  --color-bg-surface-alt: #edf2f7;
  --color-bg-subtle: #f8f9fa;
  --color-border: #e2e8f0;
  --color-border-strong: #cbd5e0;
  --color-text-primary: #1a202c;
  --color-text-secondary: #718096;
  --color-text-tertiary: #a0aec0;

  /* Semantic Colors */
  --color-success: #38a169;
  --color-success-light: #f0fff4;
  --color-success-border: #c6f6d5;
  --color-warning: #d69e2e;
  --color-warning-light: #fffff0;
  --color-warning-border: #fefcbf;
  --color-danger: #e53e3e;
  --color-danger-light: #fff5f5;
  --color-danger-border: #fed7d7;
  --color-info: #3182ce;
  --color-info-light: #ebf8ff;
  --color-info-border: #bee3f8;

  /* Typography */
  --font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
  --font-mono: 'SF Mono', 'Consolas', 'Monaco', monospace;
  --font-size-xs: 0.75rem;
  --font-size-sm: 0.875rem;
  --font-size-base: 0.9375rem;
  --font-size-lg: 1.125rem;
  --font-size-xl: 1.25rem;
  --font-size-2xl: 1.5rem;
  --font-size-3xl: 1.875rem;

  /* Spacing */
  --space-1: 4px;
  --space-2: 8px;
  --space-3: 12px;
  --space-4: 16px;
  --space-5: 20px;
  --space-6: 24px;
  --space-8: 32px;
  --space-10: 40px;
  --space-12: 48px;

  /* Borders & Shadows */
  --radius-sm: 4px;
  --radius-md: 6px;
  --radius-lg: 8px;
  --radius-xl: 12px;
  --shadow-sm: 0 1px 2px rgba(0, 0, 0, 0.05);
  --shadow-base: 0 1px 3px rgba(0, 0, 0, 0.08), 0 1px 2px rgba(0, 0, 0, 0.04);
  --shadow-md: 0 4px 6px rgba(0, 0, 0, 0.04), 0 2px 4px rgba(0, 0, 0, 0.06);
  --shadow-lg: 0 10px 15px rgba(0, 0, 0, 0.04), 0 4px 6px rgba(0, 0, 0, 0.05);
  --shadow-modal: 0 20px 25px rgba(0, 0, 0, 0.1), 0 10px 10px rgba(0, 0, 0, 0.04);

  /* Transitions */
  --transition-fast: 150ms ease;
  --transition-base: 200ms ease;
  --transition-slow: 300ms ease;
}

/* --- 2. Reset & Base --- */
*, *::before, *::after {
  box-sizing: border-box;
}

body {
  font-family: var(--font-family);
  font-size: var(--font-size-base);
  font-weight: 400;
  line-height: 1.5;
  color: var(--color-text-primary);
  background-color: var(--color-bg-page);
  margin: 0;
  padding: 0;
  padding-bottom: 50px;
  min-height: 100vh;
  -webkit-font-smoothing: antialiased;
  -moz-osx-font-smoothing: grayscale;
}

/* --- 3. Auth Page Layout --- */
body.pgx-auth-page {
  background: linear-gradient(135deg, #1a365d 0%, #2c5282 100%);
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 20px;
}

.pgx-auth-container {
  background: var(--color-bg-surface);
  border-radius: var(--radius-xl);
  box-shadow: var(--shadow-lg);
  padding: var(--space-10);
  width: 100%;
  max-width: 450px;
}

.pgx-auth-container.pgx-auth-wide {
  max-width: 550px;
}

.pgx-auth-header {
  text-align: center;
  margin-bottom: var(--space-8);
}

.pgx-auth-header h1 {
  color: var(--color-primary-900);
  font-weight: 700;
  font-size: var(--font-size-2xl);
  margin-bottom: var(--space-2);
}

.pgx-auth-header p {
  color: var(--color-text-secondary);
  margin: 0;
  font-size: var(--font-size-sm);
}

.pgx-auth-header .pgx-logo {
  font-size: var(--font-size-3xl);
  letter-spacing: -0.5px;
}

.pgx-auth-header .pgx-shield-icon {
  font-size: 3rem;
  color: var(--color-primary-700);
  margin-bottom: var(--space-4);
  display: block;
}

/* Auth buttons */
.pgx-btn-auth {
  background: var(--color-primary-900);
  border: none;
  color: white;
  padding: var(--space-3);
  font-weight: 600;
  font-size: var(--font-size-base);
  width: 100%;
  border-radius: var(--radius-md);
  cursor: pointer;
  transition: background var(--transition-fast);
}

.pgx-btn-auth:hover {
  background: var(--color-primary-700);
  color: white;
}

.pgx-btn-cancel {
  background: #64748b;
  border: none;
  color: white;
  padding: var(--space-3);
  font-weight: 600;
  font-size: var(--font-size-base);
  width: 100%;
  border-radius: var(--radius-md);
  margin-top: var(--space-2);
  cursor: pointer;
  transition: background var(--transition-fast);
  text-decoration: none;
  display: block;
  text-align: center;
}

.pgx-btn-cancel:hover {
  background: #475569;
  color: white;
}

/* Auth form inputs */
.pgx-auth-container .form-control:focus {
  border-color: var(--color-primary-500);
  box-shadow: 0 0 0 3px rgba(49, 130, 206, 0.15);
}

.pgx-code-input {
  font-size: 1.8em;
  letter-spacing: 8px;
  text-align: center;
  padding: 15px;
  font-weight: 600;
  font-family: var(--font-mono);
}

/* Auth info boxes */
.pgx-instructions {
  background: var(--color-info-light);
  border-left: 3px solid var(--color-primary-500);
  padding: var(--space-4);
  margin-bottom: var(--space-5);
  border-radius: var(--radius-sm);
  font-size: var(--font-size-sm);
}

.pgx-instructions ol {
  margin: var(--space-2) 0 0 0;
  padding-left: 20px;
}

.pgx-instructions li {
  margin-bottom: var(--space-2);
}

.pgx-warning-box {
  background: var(--color-warning-light);
  border: 1px solid var(--color-warning-border);
  border-radius: var(--radius-lg);
  padding: var(--space-4);
  margin-top: var(--space-5);
  font-size: var(--font-size-sm);
}

.pgx-warning-box strong {
  color: #92400e;
}

.pgx-secret-key {
  background: var(--color-bg-surface-alt);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  padding: var(--space-4);
  margin: var(--space-5) 0;
  text-align: center;
}

.pgx-secret-key code {
  font-size: 1.1em;
  color: var(--color-primary-900);
  font-weight: 600;
  letter-spacing: 2px;
  font-family: var(--font-mono);
}

.pgx-qr-container {
  text-align: center;
  padding: var(--space-6);
  background: var(--color-bg-surface-alt);
  border-radius: var(--radius-lg);
  margin-bottom: var(--space-6);
}

.pgx-qr-container img {
  max-width: 250px;
  border: 2px solid var(--color-primary-500);
  border-radius: var(--radius-lg);
  padding: 10px;
  background: white;
}

.pgx-help-text {
  background: var(--color-info-light);
  border-left: 3px solid var(--color-primary-500);
  padding: var(--space-3);
  margin-top: var(--space-5);
  border-radius: var(--radius-sm);
  font-size: var(--font-size-sm);
}

/* Lockout timer */
.pgx-lockout-timer {
  background: var(--color-danger-light);
  border: 1px solid var(--color-danger-border);
  border-radius: var(--radius-lg);
  padding: var(--space-5);
  text-align: center;
  margin-bottom: var(--space-5);
}

.pgx-lockout-timer h4 {
  color: var(--color-danger);
  margin-bottom: var(--space-2);
  font-weight: 600;
}

.pgx-lockout-timer .pgx-countdown {
  font-size: 2em;
  font-weight: 700;
  color: var(--color-danger);
  font-family: var(--font-mono);
}

.pgx-lockout-timer p {
  color: var(--color-text-secondary);
  margin-top: var(--space-2);
  font-size: var(--font-size-sm);
  margin-bottom: 0;
}

/* Version info */
.pgx-version-info {
  text-align: center;
  margin-top: var(--space-5);
  color: var(--color-text-tertiary);
  font-size: var(--font-size-xs);
}

/* --- 4. Application Header --- */
.pgx-header {
  background: linear-gradient(135deg, #2c5aa0 0%, #1e3d72 100%);
  color: white;
  padding: var(--space-5) var(--space-6);
}

.pgx-header h2 {
  margin: 0;
  font-weight: 600;
  font-size: var(--font-size-xl);
}

.pgx-header p {
  margin: var(--space-1) 0 0 0;
  opacity: 0.85;
  font-size: var(--font-size-sm);
}

.pgx-header-inner {
  display: flex;
  justify-content: space-between;
  align-items: center;
  max-width: 100%;
}

.pgx-header-actions a,
.pgx-header-actions .btn {
  margin-left: var(--space-2);
}

/* Centered header variant (for non-dashboard pages) */
.pgx-header-centered {
  background: linear-gradient(135deg, #2c5aa0 0%, #1e3d72 100%);
  color: white;
  padding: var(--space-6) var(--space-8);
  text-align: center;
  border-radius: var(--radius-xl) var(--radius-xl) 0 0;
}

.pgx-header-centered h1 {
  margin: 0;
  font-weight: 600;
  font-size: var(--font-size-2xl);
}

.pgx-header-centered p {
  margin: var(--space-2) 0 0 0;
  opacity: 0.85;
  font-size: var(--font-size-sm);
}

/* --- 5. Navigation --- */
.pgx-nav-buttons {
  display: flex;
  gap: var(--space-2);
  padding: var(--space-3) var(--space-5);
  background: var(--color-bg-surface-alt);
  border-bottom: 1px solid var(--color-border);
}

.pgx-nav-btn {
  display: inline-flex;
  align-items: center;
  gap: var(--space-2);
  padding: var(--space-2) var(--space-4);
  border: 1px solid var(--color-border-strong);
  border-radius: var(--radius-md);
  background: var(--color-bg-surface);
  color: var(--color-text-primary);
  text-decoration: none;
  font-size: var(--font-size-sm);
  font-weight: 500;
  cursor: pointer;
  transition: all var(--transition-fast);
}

.pgx-nav-btn:hover {
  background: var(--color-primary-100);
  border-color: var(--color-primary-500);
  color: var(--color-primary-700);
}

/* Tab navigation */
.pgx-tab-navigation {
  display: flex;
  overflow-x: auto;
  background: var(--color-bg-surface);
  border-bottom: 2px solid var(--color-border);
  padding: 0 var(--space-5);
  gap: 0;
}

.pgx-tab-button {
  padding: var(--space-3) var(--space-5);
  border: none;
  background: transparent;
  color: var(--color-text-secondary);
  font-weight: 500;
  font-size: var(--font-size-sm);
  cursor: pointer;
  border-bottom: 3px solid transparent;
  margin-bottom: -2px;
  white-space: nowrap;
  transition: all var(--transition-fast);
  display: flex;
  align-items: center;
  gap: var(--space-2);
}

.pgx-tab-button:hover {
  color: var(--color-primary-700);
  background: var(--color-bg-subtle);
}

.pgx-tab-button.active {
  color: var(--color-primary-700);
  border-bottom-color: var(--color-primary-600);
  font-weight: 600;
}

/* --- 6. Page Container --- */
.pgx-page-container {
  background: var(--color-bg-surface);
  max-width: 1400px;
  margin: var(--space-8) auto;
  border-radius: var(--radius-xl);
  box-shadow: var(--shadow-base);
  border: 1px solid var(--color-border);
  overflow: hidden;
}

.pgx-page-container-md {
  max-width: 1200px;
}

.pgx-page-container-sm {
  max-width: 900px;
}

.pgx-page-body {
  padding: var(--space-6) var(--space-8);
}

/* --- 7. Cards & Surfaces --- */
.pgx-card {
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  box-shadow: var(--shadow-sm);
}

.pgx-card-padded {
  padding: var(--space-5);
}

/* Metric cards */
.pgx-metric-card {
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  padding: var(--space-5);
  margin-bottom: var(--space-5);
  box-shadow: var(--shadow-sm);
  transition: all var(--transition-base);
}

.pgx-metric-card:hover {
  box-shadow: var(--shadow-md);
  transform: translateY(-1px);
}

.pgx-metric-value {
  font-size: 2.25rem;
  font-weight: 700;
  color: var(--color-primary-900);
  line-height: 1.2;
}

.pgx-metric-label {
  color: var(--color-text-secondary);
  font-size: var(--font-size-xs);
  text-transform: uppercase;
  font-weight: 600;
  letter-spacing: 0.5px;
}

.pgx-metric-icon {
  font-size: 2.5rem;
  color: var(--color-primary-500);
  opacity: 0.25;
}

/* Patient cards (left accent) */
.pgx-patient-card {
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-left: 3px solid var(--color-primary-600);
  border-radius: var(--radius-lg);
  padding: var(--space-4);
  margin-bottom: var(--space-3);
  transition: all var(--transition-base);
  cursor: pointer;
}

.pgx-patient-card:hover {
  box-shadow: var(--shadow-md);
  border-left-color: var(--color-primary-500);
}

/* Subsection cards */
.pgx-subsection {
  background: var(--color-bg-surface-alt);
  border-top: 3px solid var(--color-primary-600);
  border-radius: var(--radius-lg);
  padding: var(--space-5);
  margin-bottom: var(--space-5);
}

/* --- 8. Buttons --- */
.pgx-btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: var(--space-2);
  padding: var(--space-2) var(--space-4);
  border: none;
  border-radius: var(--radius-md);
  font-weight: 500;
  font-size: var(--font-size-sm);
  font-family: var(--font-family);
  cursor: pointer;
  transition: all var(--transition-fast);
  text-decoration: none;
  line-height: 1.5;
}

.pgx-btn-primary {
  background: var(--color-primary-900);
  color: white;
}
.pgx-btn-primary:hover {
  background: var(--color-primary-700);
  color: white;
}

.pgx-btn-success {
  background: var(--color-success);
  color: white;
}
.pgx-btn-success:hover {
  background: #2f855a;
  color: white;
}

.pgx-btn-danger {
  background: var(--color-danger);
  color: white;
}
.pgx-btn-danger:hover {
  background: #c53030;
  color: white;
}

.pgx-btn-outline {
  background: var(--color-bg-surface);
  color: var(--color-primary-700);
  border: 1px solid var(--color-primary-700);
}
.pgx-btn-outline:hover {
  background: var(--color-primary-100);
}

.pgx-btn-secondary {
  background: #64748b;
  color: white;
}
.pgx-btn-secondary:hover {
  background: #475569;
  color: white;
}

.pgx-btn-lg {
  padding: var(--space-3) var(--space-6);
  font-size: var(--font-size-base);
}

.pgx-btn-sm {
  padding: var(--space-1) var(--space-3);
  font-size: var(--font-size-xs);
}

/* Submit button (main form action) */
.pgx-btn-submit {
  background: var(--color-success);
  color: white;
  padding: var(--space-3) var(--space-8);
  font-weight: 600;
  font-size: var(--font-size-base);
  border: none;
  border-radius: var(--radius-md);
  cursor: pointer;
  transition: all var(--transition-fast);
}

.pgx-btn-submit:hover {
  background: #2f855a;
}

/* Save button */
.pgx-btn-save {
  background: var(--color-primary-500);
  color: white;
  padding: var(--space-2) var(--space-5);
  font-weight: 500;
  border: none;
  border-radius: var(--radius-md);
  cursor: pointer;
  transition: all var(--transition-fast);
}

.pgx-btn-save:hover {
  background: var(--color-primary-700);
}

/* --- 9. Forms & Inputs --- */
.pgx-form-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
  gap: var(--space-5);
}

.pgx-form-grid-2 {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: var(--space-5);
}

.pgx-form-grid-3 {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  gap: var(--space-5);
}

.pgx-form-group {
  display: flex;
  flex-direction: column;
  gap: var(--space-1);
}

.pgx-form-label {
  font-weight: 500;
  font-size: var(--font-size-sm);
  color: var(--color-text-primary);
}

.pgx-form-input,
.pgx-form-select,
.pgx-form-textarea {
  padding: var(--space-3);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-md);
  font-family: var(--font-family);
  font-size: var(--font-size-base);
  color: var(--color-text-primary);
  background: var(--color-bg-surface);
  transition: border-color var(--transition-fast), box-shadow var(--transition-fast);
  width: 100%;
}

.pgx-form-input:focus,
.pgx-form-select:focus,
.pgx-form-textarea:focus {
  outline: none;
  border-color: var(--color-primary-500);
  box-shadow: 0 0 0 3px rgba(49, 130, 206, 0.15);
}

.pgx-form-input[readonly] {
  background: var(--color-bg-surface-alt);
  color: var(--color-text-secondary);
}

.pgx-form-section h3 {
  color: var(--color-primary-900);
  font-weight: 600;
  font-size: var(--font-size-lg);
  margin-bottom: var(--space-4);
  padding-bottom: var(--space-2);
  border-bottom: 2px solid var(--color-border);
}

/* --- 10. Tables --- */
.pgx-table {
  width: 100%;
  border-collapse: separate;
  border-spacing: 0;
  border-radius: var(--radius-lg);
  overflow: hidden;
  border: 1px solid var(--color-border);
}

.pgx-table thead {
  background: var(--color-bg-surface-alt);
}

.pgx-table th {
  padding: var(--space-3) var(--space-4);
  text-align: left;
  font-weight: 600;
  font-size: var(--font-size-sm);
  color: var(--color-text-primary);
  border-bottom: 2px solid var(--color-border);
  white-space: nowrap;
}

.pgx-table td {
  padding: var(--space-3) var(--space-4);
  border-bottom: 1px solid var(--color-border);
  font-size: var(--font-size-sm);
}

.pgx-table tbody tr:last-child td {
  border-bottom: none;
}

.pgx-table tbody tr:hover {
  background: var(--color-bg-subtle);
}

/* --- 11. Badges & Status --- */
.pgx-badge {
  display: inline-flex;
  align-items: center;
  padding: 2px var(--space-3);
  border-radius: 10px;
  font-size: var(--font-size-xs);
  font-weight: 500;
}

.pgx-badge-primary {
  background: var(--color-primary-100);
  color: var(--color-primary-900);
}

.pgx-badge-success {
  background: var(--color-success-light);
  color: #276749;
}

.pgx-badge-danger {
  background: var(--color-danger-light);
  color: #c53030;
}

.pgx-badge-info {
  background: var(--color-info-light);
  color: var(--color-primary-900);
}

.pgx-badge-warning {
  background: var(--color-warning-light);
  color: #92400e;
}

.pgx-badge-secondary {
  background: var(--color-bg-surface-alt);
  color: var(--color-text-secondary);
}

/* --- 12. Modals --- */
.pgx-modal-overlay {
  display: none;
  position: fixed;
  top: 0;
  left: 0;
  width: 100%;
  height: 100%;
  background: rgba(0, 0, 0, 0.5);
  z-index: 1000;
  align-items: center;
  justify-content: center;
}

.pgx-modal-overlay.active {
  display: flex;
}

.pgx-modal-content {
  background: var(--color-bg-surface);
  border-radius: var(--radius-xl);
  box-shadow: var(--shadow-modal);
  max-width: 500px;
  width: 90%;
  max-height: 90vh;
  overflow-y: auto;
  padding: var(--space-6);
}

.pgx-modal-header {
  margin-bottom: var(--space-5);
}

.pgx-modal-header h3 {
  font-weight: 600;
  margin: 0;
  color: var(--color-text-primary);
}

.pgx-modal-actions {
  display: flex;
  gap: var(--space-3);
  justify-content: flex-end;
  margin-top: var(--space-6);
}

/* --- 13. Alerts & Messages --- */
.pgx-alert {
  padding: var(--space-3) var(--space-4);
  border-radius: var(--radius-lg);
  margin-bottom: var(--space-4);
  font-size: var(--font-size-sm);
  border: 1px solid transparent;
}

.pgx-alert-success {
  background: var(--color-success-light);
  border-color: var(--color-success-border);
  color: #276749;
}

.pgx-alert-danger {
  background: var(--color-danger-light);
  border-color: var(--color-danger-border);
  color: #c53030;
}

.pgx-alert-warning {
  background: var(--color-warning-light);
  border-color: var(--color-warning-border);
  color: #92400e;
}

.pgx-alert-info {
  background: var(--color-info-light);
  border-color: var(--color-info-border);
  color: var(--color-primary-900);
}

/* --- 14. Loading & Spinners --- */
@keyframes pgx-spin {
  0% { transform: rotate(0deg); }
  100% { transform: rotate(360deg); }
}

@keyframes pgx-fadeIn {
  from { opacity: 0; transform: translateY(10px); }
  to { opacity: 1; transform: translateY(0); }
}

@keyframes pgx-slideDown {
  from { opacity: 0; max-height: 0; }
  to { opacity: 1; max-height: 500px; }
}

.pgx-spinner {
  border: 4px solid var(--color-border);
  border-top: 4px solid var(--color-primary-600);
  border-radius: 50%;
  width: 40px;
  height: 40px;
  animation: pgx-spin 0.8s linear infinite;
  margin: 0 auto;
}

.pgx-spinner-sm {
  width: 24px;
  height: 24px;
  border-width: 3px;
}

.pgx-spinner-lg {
  width: 60px;
  height: 60px;
  border-width: 5px;
}

.pgx-loading-overlay {
  position: fixed;
  top: 0;
  left: 0;
  width: 100%;
  height: 100%;
  background: rgba(255, 255, 255, 0.92);
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  z-index: 2000;
  gap: var(--space-4);
}

.pgx-loading-overlay p {
  color: var(--color-text-secondary);
  font-weight: 500;
}

/* --- 15. Disclaimer Modal --- */
.pgx-disclaimer-overlay {
  display: none;
  position: fixed;
  top: 0;
  left: 0;
  width: 100%;
  height: 100%;
  background: rgba(0, 0, 0, 0.8);
  backdrop-filter: blur(8px);
  z-index: 3000;
  align-items: center;
  justify-content: center;
}

.pgx-disclaimer-overlay.active {
  display: flex;
}

.pgx-disclaimer-content {
  background: var(--color-bg-surface);
  border-radius: var(--radius-xl);
  max-width: 700px;
  width: 90%;
  max-height: 85vh;
  overflow-y: auto;
  box-shadow: var(--shadow-modal);
}

.pgx-disclaimer-header {
  background: var(--color-danger);
  color: white;
  padding: var(--space-5);
  text-align: center;
  border-radius: var(--radius-xl) var(--radius-xl) 0 0;
}

.pgx-disclaimer-header h2 {
  margin: 0;
  font-weight: 600;
}

.pgx-disclaimer-body {
  padding: var(--space-6);
}

.pgx-disclaimer-actions {
  display: flex;
  gap: var(--space-3);
  justify-content: center;
  padding: var(--space-5);
  border-top: 1px solid var(--color-border);
}

.pgx-disclaimer-section {
  margin-bottom: var(--space-4);
}

.pgx-disclaimer-section h3 {
  color: var(--color-primary-600);
  font-size: var(--font-size-sm);
  font-weight: 600;
  margin-bottom: var(--space-1);
  padding-bottom: var(--space-1);
  border-bottom: 2px solid var(--color-border);
}

.pgx-disclaimer-section p {
  color: var(--color-text-secondary);
  line-height: 1.5;
  font-size: var(--font-size-sm);
  margin: 0;
}

/* --- 16. Gene Accordion --- */
.pgx-gene-accordion {
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  margin-bottom: var(--space-3);
  overflow: hidden;
}

.pgx-gene-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--space-3) var(--space-4);
  background: var(--color-bg-surface);
  cursor: pointer;
  transition: background var(--transition-fast);
  border: none;
  width: 100%;
  text-align: left;
}

.pgx-gene-header:hover {
  background: var(--color-bg-subtle);
}

.pgx-gene-header.active {
  background: var(--color-primary-100);
  border-bottom: 1px solid var(--color-border);
}

.pgx-gene-title {
  font-weight: 600;
  color: var(--color-primary-900);
  font-size: var(--font-size-base);
}

.pgx-gene-drugs {
  color: var(--color-text-secondary);
  font-size: var(--font-size-xs);
}

.pgx-gene-arrow {
  color: var(--color-text-tertiary);
  transition: transform var(--transition-base);
  font-size: var(--font-size-sm);
}

.pgx-gene-header.active .pgx-gene-arrow {
  transform: rotate(90deg);
}

.pgx-gene-body {
  padding: var(--space-4);
  background: var(--color-bg-surface);
}

/* --- 17. Chat / ChatIQ --- */
.pgx-chat-layout {
  display: flex;
  gap: var(--space-5);
  height: calc(100vh - 160px);
  padding: var(--space-5);
}

.pgx-chat-sidebar {
  width: 280px;
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-xl);
  display: flex;
  flex-direction: column;
  overflow: hidden;
}

.pgx-chat-sidebar-header {
  background: var(--color-primary-900);
  color: white;
  padding: var(--space-4);
  font-weight: 600;
  display: flex;
  align-items: center;
  gap: var(--space-2);
}

.pgx-conversation-item {
  padding: var(--space-3) var(--space-4);
  cursor: pointer;
  border-bottom: 1px solid var(--color-border);
  transition: background var(--transition-fast);
  font-size: var(--font-size-sm);
}

.pgx-conversation-item:hover {
  background: var(--color-bg-subtle);
}

.pgx-conversation-item.active {
  background: var(--color-primary-900);
  color: white;
}

.pgx-chat-main {
  flex: 1;
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-xl);
  display: flex;
  flex-direction: column;
  overflow: hidden;
}

.pgx-chat-header {
  background: var(--color-primary-900);
  color: white;
  padding: var(--space-4);
  font-weight: 600;
  display: flex;
  align-items: center;
  gap: var(--space-2);
}

.pgx-chat-messages {
  flex: 1;
  overflow-y: auto;
  padding: var(--space-5);
}

.pgx-message {
  margin-bottom: var(--space-4);
  display: flex;
}

.pgx-message-user {
  justify-content: flex-end;
}

.pgx-message-bubble {
  max-width: 70%;
  padding: var(--space-3) var(--space-4);
  border-radius: var(--radius-lg);
  font-size: var(--font-size-sm);
  line-height: 1.6;
}

.pgx-message-user .pgx-message-bubble {
  background: var(--color-primary-700);
  color: white;
}

.pgx-message-assistant .pgx-message-bubble {
  background: var(--color-bg-surface-alt);
  border: 1px solid var(--color-border);
  color: var(--color-text-primary);
}

.pgx-chat-input-area {
  padding: var(--space-4);
  border-top: 1px solid var(--color-border);
  display: flex;
  gap: var(--space-3);
}

.pgx-chat-input {
  flex: 1;
  padding: var(--space-3);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-md);
  font-family: var(--font-family);
  font-size: var(--font-size-base);
  resize: none;
}

.pgx-chat-input:focus {
  outline: none;
  border-color: var(--color-primary-500);
  box-shadow: 0 0 0 3px rgba(49, 130, 206, 0.15);
}

.pgx-chat-send {
  background: var(--color-primary-700);
  color: white;
  border: none;
  border-radius: var(--radius-md);
  padding: var(--space-3) var(--space-5);
  font-weight: 500;
  cursor: pointer;
  transition: background var(--transition-fast);
}

.pgx-chat-send:hover {
  background: var(--color-primary-900);
}

/* --- 18. Metrics & Dashboard --- */
.pgx-stats-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
  gap: var(--space-4);
}

.pgx-stat-card {
  background: var(--color-bg-surface);
  border: 1px solid var(--color-border);
  border-top: 3px solid var(--color-primary-600);
  border-radius: var(--radius-lg);
  padding: var(--space-4);
  text-align: center;
}

.pgx-stat-value {
  font-size: var(--font-size-2xl);
  font-weight: 700;
  color: var(--color-primary-900);
}

.pgx-stat-label {
  color: var(--color-text-secondary);
  font-size: var(--font-size-xs);
  text-transform: uppercase;
  font-weight: 500;
}

/* Quick action cards */
.pgx-quick-actions {
  display: flex;
  gap: var(--space-2);
  flex-wrap: wrap;
}

/* --- 19. Upload / Drop Zone --- */
.pgx-drop-zone {
  border: 2px dashed var(--color-border-strong);
  border-radius: var(--radius-xl);
  padding: var(--space-10);
  text-align: center;
  transition: all var(--transition-base);
  cursor: pointer;
  background: var(--color-bg-surface);
}

.pgx-drop-zone:hover,
.pgx-drop-zone.drag-over {
  border-color: var(--color-primary-500);
  background: var(--color-primary-100);
}

.pgx-drop-zone i {
  font-size: 2.5rem;
  color: var(--color-primary-500);
  margin-bottom: var(--space-3);
  display: block;
}

.pgx-drop-zone p {
  color: var(--color-text-secondary);
  margin: var(--space-2) 0;
}

/* File items */
.pgx-file-item {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--space-3) var(--space-4);
  border: 1px solid var(--color-border);
  border-left: 3px solid var(--color-primary-600);
  border-radius: var(--radius-md);
  margin-bottom: var(--space-2);
  background: var(--color-bg-surface);
}

/* --- 20. Verbose Log Modal --- */
.pgx-verbose-overlay {
  display: none;
  position: fixed;
  top: 0;
  left: 0;
  width: 100%;
  height: 100%;
  background: rgba(0, 0, 0, 0.7);
  z-index: 2000;
  align-items: center;
  justify-content: center;
}

.pgx-verbose-overlay.active {
  display: flex;
}

.pgx-verbose-content {
  background: #1e1e2e;
  border-radius: var(--radius-xl);
  width: 90%;
  max-width: 900px;
  max-height: 85vh;
  overflow-y: auto;
  box-shadow: var(--shadow-modal);
}

.pgx-verbose-header {
  background: var(--color-warning);
  color: white;
  padding: var(--space-4) var(--space-5);
  display: flex;
  justify-content: space-between;
  align-items: center;
  border-radius: var(--radius-xl) var(--radius-xl) 0 0;
}

.pgx-verbose-header h3 {
  margin: 0;
  font-weight: 600;
}

.pgx-verbose-body {
  padding: var(--space-5);
  color: #d4d4d4;
  font-family: var(--font-mono);
  font-size: var(--font-size-sm);
  line-height: 1.8;
}

/* Progress indicator bar */
.pgx-progress-bar {
  display: flex;
  align-items: center;
  gap: var(--space-2);
  padding: var(--space-3) var(--space-5);
  background: var(--color-bg-surface-alt);
  border-bottom: 1px solid var(--color-border);
}

.pgx-progress-step {
  display: flex;
  align-items: center;
  gap: var(--space-1);
  font-size: var(--font-size-xs);
  color: var(--color-text-tertiary);
}

.pgx-progress-step.active {
  color: var(--color-primary-700);
  font-weight: 600;
}

.pgx-progress-step.completed {
  color: var(--color-success);
}

.pgx-progress-connector {
  width: 24px;
  height: 2px;
  background: var(--color-border);
}

.pgx-progress-step.completed + .pgx-progress-connector {
  background: var(--color-success);
}

/* --- 21. Bootstrap Overrides --- */
.btn-primary {
  background-color: var(--color-primary-900) !important;
  border-color: var(--color-primary-900) !important;
}
.btn-primary:hover, .btn-primary:focus {
  background-color: var(--color-primary-700) !important;
  border-color: var(--color-primary-700) !important;
}

.bg-primary {
  background-color: var(--color-primary-900) !important;
}

.text-primary {
  color: var(--color-primary-700) !important;
}

.btn-outline-primary {
  color: var(--color-primary-700) !important;
  border-color: var(--color-primary-700) !important;
}
.btn-outline-primary:hover {
  background-color: var(--color-primary-700) !important;
  border-color: var(--color-primary-700) !important;
  color: white !important;
}

.btn-success {
  background-color: var(--color-success) !important;
  border-color: var(--color-success) !important;
}
.btn-success:hover {
  background-color: #2f855a !important;
  border-color: #2f855a !important;
}

.btn-info {
  background-color: var(--color-info) !important;
  border-color: var(--color-info) !important;
  color: white !important;
}
.btn-info:hover {
  background-color: var(--color-primary-700) !important;
  border-color: var(--color-primary-700) !important;
}

.btn-danger {
  background-color: var(--color-danger) !important;
  border-color: var(--color-danger) !important;
}

.badge.bg-info {
  background-color: var(--color-info) !important;
}
.badge.bg-success {
  background-color: var(--color-success) !important;
}
.badge.bg-danger {
  background-color: var(--color-danger) !important;
}
.badge.bg-primary {
  background-color: var(--color-primary-900) !important;
}

.card {
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg) !important;
  box-shadow: var(--shadow-sm);
}

.card-header.bg-primary {
  background: var(--color-primary-900) !important;
  border-bottom: 1px solid var(--color-border);
}

.form-control:focus,
.form-select:focus {
  border-color: var(--color-primary-500);
  box-shadow: 0 0 0 3px rgba(49, 130, 206, 0.15);
}

.table > thead {
  background-color: var(--color-bg-surface-alt);
}

.table > thead > tr > th {
  color: var(--color-text-primary);
  font-weight: 600;
  border-bottom: 2px solid var(--color-border);
}

.nav-tabs .nav-link.active {
  background-color: var(--color-primary-900) !important;
  color: white !important;
  border-color: var(--color-primary-900) !important;
}

.nav-tabs .nav-link {
  color: var(--color-text-secondary);
  font-weight: 500;
}

.nav-tabs .nav-link:hover {
  color: var(--color-primary-700);
}

.alert {
  border-radius: var(--radius-lg);
}

/* --- 22. Responsive --- */
@media (max-width: 576px) {
  .pgx-header {
    padding: var(--space-4);
  }
  .pgx-header-inner {
    flex-direction: column;
    gap: var(--space-3);
    text-align: center;
  }
  .pgx-nav-buttons {
    flex-direction: column;
  }
  .pgx-modal-content {
    width: 95%;
    padding: var(--space-4);
  }
  .pgx-auth-container {
    padding: var(--space-6);
  }
}

@media (max-width: 768px) {
  .pgx-form-grid,
  .pgx-form-grid-2,
  .pgx-form-grid-3 {
    grid-template-columns: 1fr;
  }
  .pgx-tab-navigation {
    flex-wrap: nowrap;
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
  }
  .pgx-page-container {
    margin: var(--space-2);
    border-radius: var(--radius-lg);
  }
  .pgx-page-body {
    padding: var(--space-4);
  }
  .pgx-chat-layout {
    flex-direction: column;
    height: auto;
  }
  .pgx-chat-sidebar {
    width: 100%;
    max-height: 200px;
  }
}

@media (max-width: 992px) {
  .pgx-chat-layout {
    flex-direction: column;
  }
  .pgx-chat-sidebar {
    width: 100%;
    max-height: 250px;
  }
}

/* --- 23. Print --- */
@media print {
  body {
    background: white;
  }
  .pgx-header,
  .pgx-nav-buttons,
  .pgx-tab-navigation,
  .pgx-disclaimer-overlay,
  .pgx-verbose-overlay,
  .pgx-loading-overlay {
    display: none !important;
  }
  .pgx-page-container {
    box-shadow: none;
    border: none;
    margin: 0;
  }
}